Bone marrow is essentially a type of spongy
tissue found internal to a bone, capable and bestowed with a job of generating
blood stem cells. These stem cells later mature into full grown blood cells and
join the blood stream to circulate.
Onset
and occurrence of disease
Generally these cells are found in the
bones which are long and therefore contains a lot of spongy tissues, enough for
hosting the marrow to produce such stem cells to help produce blood. Often,
this area is hit by cancerous cells, which rapidly divide and hence kill and
mutate the healthy marrow cells in the vicinity and therefore inhibit the
production of healthy blood cells. This therefore require transplantation
operation on the patient.
Transplantation
requirement and related procurement
Quite often, the bone marrow transplant
operation is advised to patients in order to replace and effectively get rid of
damaged cells of bone marrow with healthy stem cells to facilitate generation
of healthy blood cells again. This being a complex surgical procedure, requires
utmost operational expertise to ensure that the patient is treated with top
notch care and support. The primary difference between this and other general
operation lay in the longer recovery and stabilisation phase related to bone marrow
transplantation.
Present
scenario of transplantation in India
India has essentially become the new formed
pit-stop for the majority of all bone marrow transplantation operations. The
rapid reduction on overall Bone Marrow Transplant in India cost including operational procedures
and the ease of post operational care makes India one of the leading realms for
this complex procedure. The recent development in the medical scenario as well
as the advanced medication and machinery ensures that the patients get the best
of treatments as compared to the other parts of the world.
Cost
factor associated and related parameters
Due to the complexity associated, the
medication related to this life saving operation is also quite complicated in
its own accord. The medication usually can be within the range of 10 to 36
lakhs and often redeemed free on account of some trusts too. The medication
completely depends on the nature of bone marrow transplant in question and also
on the severity of the operation in question. The category of hospital also
plays a major part in these extremely crucial operations.
Types
of transplantation in broad sense
The mode of transplantation may be broadly
classified into two genres, one being Autologous transplantation and other one
being Allogeneic transplantation. The
first one revolved around the transplantation of stem cells extracted from the
very patient body and reinserted into the target area. The Allogeneic, however,
is about the transplantation of the bone marrow, sourced from the body of a
different individual, who has been matched with the patient stem cell. This one
stands the best ground for success in the long run. Therefore, in majority of
such operational procedures, the doctors usually prefer matching of stem cells
from a donor, followed by grafting to ensure a smoother operation with minimal
post operational side effects and better chances of success.